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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Dab1 rabbit polyclonal antibody |
Gene Name: | Disabled homolog 1 |
Synonyms: | Dab1, Scrambler, Scm, Scr, Yot, Yotari |
Immunogen: | Recombinant protein corresponding to Mouse Dab1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 64 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | O75553, P97318 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | small intestine, cerebellum |
Background
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Images
 | Western blot analysis of Dab1 (GB112179) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
