Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Deformed epidermal autoregulatory factor 1 homolog |
Synonyms: | DEAF1, NUDR, SPN, Suppressin, ZMYND5 |
Immunogen: | Recombinant protein corresponding to Mouse Deformed Epidermal Autoregulatory Factor 1 |
Uniprot ID: | Q9Z1T5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 60 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | testis |
Background
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction (By similarity). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes.
Images
Western blot analysis of DEAF1 (GB114501) at dilution of 1: 1000 | |
Western blot analysis of DEAF1 (GB114501) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |