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Anti-Dnmt3b Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Dnmt3b rabbit polyclonal antibody |
Gene Name: | DNA (cytosine-5)-methyltransferase 3B |
Synonyms: | Dnmt3b, DNA methyltransferase MmuIIIB, DNA MTase MmuIIIB, M.MmuIIIB, ICF1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Dnmt3b |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 97 kDa |
Observed MW. | 97 kDa |
Uniprot ID: | Q9UBC3, O88509 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
Background
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing .
Images
| Western blot analysis of DNMT3B (GB112020) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
