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Anti-Dynamin 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dynamin-1 |
Synonyms: | DNM1, DNM 1, Dynamin-1, DNM, EIEE31, Dynamin1, Dynamin 1, Dynamin |
Immunogen: | Recombinant protein corresponding to Mouse Dynamin 1 |
Uniprot ID: | P39053 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoskeleton |
Predicted MW. / Observed MW. | 98 kDa / 98 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, cerebral cortex, cerebellum |
IHC/IF | Mouse, Rat | 1: 100-1: 1000 | brain |
Background
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15.
Images
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Western blot analysis of dynomin (GB11855) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using dynomin (GB11855) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin embedded rat brain using dynomin (GB11855) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
