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Anti-E3 SUMO-protein ligase PIAS4/PIASy Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | E3 SUMO-protein ligase PIAS4/PIASy rabbit polyclonal |
Gene Name: | E3 SUMO-protein ligase PIAS4 |
Synonyms: | PIASy, Protein inhibitor of activated STAT protein 4, PIAS-gamma, PIAS4, Piasg, ZMIZ6, PIAS4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse E3 SUMO-protein ligase PIAS4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 56 kDa |
Observed MW. | 72 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Rat | 1: 500-1: 1000 | testis |
Background
PIAS4(protein inhibitor of activated STAT protein 4) is also named as PIASG, PIASy and belongs to the PIAS family. It enhanced the conjugation of SUMO2 to GATA2 through its E3 SUMO ligase activity. TGF-b can up-regulates PLAS4 expression in MCs to down-regulatea-SMA gene transcription by the interaction with E12 and PLAS4 predominantly acts as E3 ligases for E12 in MCs among PIAS family members . This protein can be sumoylated and Lys-35 is the main site of sumoylation.
Images
 | Western blot analysis of PIASy (GB113100) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
