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| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | EH domain-containing protein 2 |
Synonyms: | EH domain containing 2, EH domain containing protein 2, EHD2, PAST homolog 2, PAST2 |
Immunogen: | Recombinant protein corresponding to Mouse EHD2 |
Uniprot ID: | Q8BH64 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 61 kDa / 70 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 3000 | lung, fat, heart |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | lung, placenta |
Background
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis . Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4 . Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane . Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane (By similarity).
Images
| Western blot analysis of EHD2 (GB114403) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using EHD2 (GB114403) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded human placenta using EHD2 (GB114403) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
