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Anti-EMP-1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EMP-1 rabbit polyclonal antibody |
Gene Name: | Epithelial membrane protein 1 |
Synonyms: | EMP-1, Tumor-associated membrane protein, Tmp, CL-20, B4B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EMP-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane |
Uniprot ID: | P47801, P54848 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 1800 | duodenum, eye, small intestine |
Background
Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion.
Images
| Immunohistochemistry of paraffin embedded human small intestine using EMP1 (GB112009) at dilution of 1:600 (300x lens) |
 | Immunohistochemistry of paraffin embedded mouse duodenum using Emp1 (GB112009) at dilution of 1:300 (300x lens) |
 | Immunohistochemistry of paraffin embedded mouse eye using Emp1 (GB112009) at dilution of 1:300 (300x lens) |
| Immunohistochemistry of paraffin embedded rat eye using EMP1 (GB112009) at dilution of 1:600 (200x lens) |
| Immunohistochemistry of paraffin embedded rat small intestine using Emp1 (GB112009) at dilution of 1:300 (250x lens) |
| Immunohistochemistry of paraffin embedded rat small intestine using EMP1 (GB112009) at dilution of 1:600 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
