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Anti-EPLIN Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EPLIN rabbit polyclonal |
Gene Name: | LIM domain and actin-binding protein 1 |
Synonyms: | EPLIN, LIM domain and actin binding 1, LIMA1, SREBP3, Epithelial protein lost in neoplasm, D15Ertd366e |
Immunogen: | Recombinant protein corresponding to Mouse EPLIN |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Cytoskeleton |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 800-1: 1600 | rectum, colon |
Background
EPLIN is a cytoskeletal protein that is preferentially expressed in epithelial cells and is implicated in regulation of cytoskeletal dynamics and cytokinesis. In human, there are two known isoforms, EPLIN-a and -b, generated by alternative promoter usage from a single gene. EPLIN-a expression is often down-regulated in cancerous cells and tissues.
Images
| Immunohistochemistry analysis of paraffin-embedded human rectum using EPLIN (GB113474) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse rectum using EPLIN (GB113474) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded rat colon using EPLIN (GB113474) at dilution of 1: 1600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
