Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | EPS8 rabbit polyclonal antibody |
Gene Name: | Epidermal growth factor receptor kinase substrate 8 |
Synonyms: | Eps8, EPS8, DFNB102, Epidermal growth factor receptor pathway substrate 8 |
Immunogen: | Recombinant protein corresponding to Mouse EPS8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 92 kDa |
Observed MW. | 97 kDa |
Uniprot ID: | Q08509 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1500 | ovary, uterus, brain |
Background
Epidermal growth factor receptor kinase substrate 8 is an enzyme which is a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Images
Western blot analysis of EPS8 (GB11739) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |