Reactivity: | H,M,R & H,M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Endostatin rabbit polyclonal |
Gene Name: | Collagen alpha-1(XVIII) chain |
Synonyms: | COL18A1, Collagen alpha 1(XVIII) chain, collagen, type XVIII, alpha 1, Endostatin, FLJ27325, FLJ34914, KNO, KNO1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Endostatin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse | 1: 500-1: 2000 | kidney, liver |
IF | Human, Mouse | 1: 500-1: 1500 | kidney, liver |
Background
Endostatin is a naturally occurring, 20-kDa C-terminal fragment derived from type XVIII collagen. It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin.
Endostatin is a broad-spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor (bFGF/FGF-2) and vascular endothelial growth factor (VEGF).
Images
Immunohistochemistry analysis of paraffin-embedded human kidney using Endostatin (GB11329) at dilution of 1:1200 |
|
Immunohistochemistry analysis of paraffin-embedded mouse liver using Endostatin (GB11329) at dilution of 1:1200 |
|
Immunohistochemistry analysis of paraffin-embedded mouse kidney using Endostatin (GB11329) at dilution of 1:1200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |