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Anti-Eph receptor B4/HTK Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HTK rabbit polyclonal antibody |
Gene Name: | Ephrin type-B receptor 4 |
Synonyms: | Hepatoma transmembrane kinase, HTK, Tyrosine-protein kinase TYRO11, EPHB4, MYK1, TYRO11 |
Immunogen: | Recombinant protein corresponding to Mouse HTK |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 108 kDa |
Observed MW. | 110-120 kDa |
Uniprot ID: | P54760 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | Jurkat, A431, K562, HepG2, MCF7 |
IHC/IF | Human | 1: 1000-1: 3000 | colon, esophagus cancer, liver cancer, thyroid cancer |
Background
EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family which binds members of the ephrin ligand family. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.
Images
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Western blot analysis of EphB4 (GB111362) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human colon using EphB4 (GB111362) at dilution of 1: 1500 (400x lens) |
| Immunohistochemistry of paraffin embedded human esophagus cancer using EphB4 (GB111362) at dilution of 1: 1500 (400x lens) |
| Immunohistochemistry of paraffin embedded human liver cancer using EphB4 (GB111362) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded human thyroid cancer using EphB4 (GB111362) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
