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Anti-Erbin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Erbin rabbit polyclonal antibody |
Gene Name: | Erbin |
Synonyms: | Densin-180-like protein, Erbb2-interacting protein, Protein LAP2, Erbin, Erbb2ip |
Immunogen: | Recombinant protein corresponding to Mouse Erbin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 157 kDa |
Observed MW. | 157 kDa |
Uniprot ID: | Q96RT1, Q80TH2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | colon, skin |
Background
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Images
| Western blot analysis of Erbin (GB111771) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
