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Anti-Estrogen Receptor alpha Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Estrogen receptor |
Synonyms: | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human ESR1 |
Uniprot ID: | P03372 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | breast cancer, cervical carcinoma, ovary |
Background
The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor.
Images
| Immunohistochemistry analysis of paraffin embedded human cervical carcinoma using ESR1 (GB121843) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using ESR1 (GB121843) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat ovary using ESR1 (GB121843) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse ovary using ESR1 (GB121843) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
