Reactivity: | H,M,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Estrogen receptor |
Synonyms: | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Estrogen Receptor alpha |
Uniprot ID: | P19785 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 66 kDa / 66 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | uterus, testis, placenta |
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | ovarian cancer, breast cancer |
Background
The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor.
Images
Western blot analysis of ER(GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using ER (GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human breast cancer using ER (GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded mouse ovary using ER (GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded rat breast using ER (GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human breast cancer using ER (GB111843) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded human endometrioid adenocarcinoma using ER (GB111843) at dilution of 1: 800 | |
Immunofluorescent analysis of 4% paraformaldehyde-fixed MCF7 cell using ER (GB111843) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded human breast cancer using ER (GB111843) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human breast cancer using ER (GB111843) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded human breast cancer using ER (GB111843) at dilution of 1: 400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |