Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Ezrin rabbit polyclonal antibody |
Gene Name: | Ezrin |
Synonyms: | Cytovillin, Villin-2, p81, EZR, VIL2, CVIL, CVL, cytovillin 2, Ezrin |
Immunogen: | Recombinant protein corresponding to Human Ezrin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | P15311 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, colon, epityphlon, kidney, ovarian cancer, stomach |
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers.
Images
Immunohistochemistry of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:3000 (400x lens) |
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Immunohistochemistry of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:6000 (400x lens) |
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Immunohistochemistry of paraffin embedded human epityphlon using EZrin (GB111200) at dilution of 1:3000 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using EZrin (GB111200) at dilution of 1:1100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using EZrin (GB111200) at dilution of 1:1100 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
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Immunofluorescence of paraffin embedded rat stomach using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |