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Anti-FBXO4/FBX4 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | F-box only protein 4 |
Synonyms: | FBX4 |
Immunogen: | Recombinant protein corresponding to Mouse FBXO4 |
Uniprot ID: | Q8CHQ0 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | colon cancer, kidney |
Background
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1 (By similarity).
Images
| Immunohistochemistry analysis of paraffin embedded human colon cancer using FBXO4 (GB114413) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using FBXO4 (GB114413) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat kidney using FBXO4 (GB114413) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
