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Anti-FBXO42 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FBXO42 rabbit polyclonal antibody |
Gene Name: | F-box only protein 42 |
Synonyms: | Fbxo42, FBX42, F box protein 42 |
Immunogen: | Recombinant protein corresponding to Mouse FBXO42 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 78 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | Q6PDJ6 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 200-1: 500 | testis, brain |
Background
FBXO42 (F-box only protein 42) is a 717 amino acid protein that contains four Kelch repeats and one N-terminal F-box domain, and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination.
Images
 | Western blot analysis of FBXO42 (GB112313) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
