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Anti-FBXO7 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FBXO7 rabbit polyclonal antibody |
Gene Name: | F-box only protein 7 |
Synonyms: | Fbxo7, FBX7, PKPS, PARK15 |
Immunogen: | Recombinant protein corresponding to Mouse FBXO7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 58 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9Y3I1 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | PC3, 293T |
Background
FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
Images
 | Western blot analysis of FBXO7 (GB112340) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
