Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FCRL5 rabbit polyclonal antibody |
Gene Name: | Fc receptor-like protein 5 |
Synonyms: | FcR-like protein 5, FcRL5, BXMAS1-like protein 2, mBXMH2, Fc receptor homolog 3, FcRH3, moFcRH3, CD307e, Fcrl5, Fcrh3 |
Immunogen: | Recombinant protein corresponding to Mouse FCRL5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q96RD9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 200-1: 1000 | gastric cancer, stomach |
Background
FCRL5, also known as CD307 or IRTA2, is a surface protein expressed selectively on B cells and plasma cells . This protein has both an immunoreceptor tyrosine-based activation motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) in its cytoplasmic region . FCRL5 is implicated in B cell development and lymphomagenesis . It may have an immunoregulatory role in marginal zone B-cells.
Images
Immunohistochemistry of paraffin embedded human gastric cancer using CD307 (GB111823) at dilution of 1:600 (300x lens) | |
Immunohistochemistry of paraffin embedded human stomach using CD307 (GB111823) at dilution of 1:1000 (300x lens) | |
Immunofluorescence of paraffin embedded human gastric cancer using CD307 (GB111823) at dilution of 1:1200 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |