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Anti-FDPS/FPS Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FDPS/FPS rabbit polyclonal |
Gene Name: | Farnesyl pyrophosphate synthase |
Synonyms: | FDPS, FPP synthase, FPPS, FPS, KIAA1293, Cholesterol-regulated 39 kDa protein, CR 39, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase |
Immunogen: | Recombinant protein corresponding to Mouse FDPS/FPS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 39 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HeLa, HUVEC, HCT116 |
Background
FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression. Western blot analysis using this antibody detected a major band around 41 kDa in mouse liver tissue.
Images
 | Western blot analysis of FDPS/FPS (GB113628) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
