Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FGF12 rabbit polyclonal antibody |
Gene Name: | Fibroblast growth factor 12 |
Synonyms: | FGF-12, Fibroblast growth factor homologous factor 1, FHF-1, Myocyte-activating factor, EIEE47, FGF12B |
Immunogen: | Recombinantproteincorrespondingto Mouse FGF12 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 27 kDa |
Observed MW. | 27 kDa |
Uniprot ID: | P61329, P61150 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex |
Background
FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members play important roles in embryogenesis, angiogenesis, and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore, FGF12 was thought to be related to nervous system development and function.
Images
Western blot analysis of FGF12 (GB111700) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |