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Anti-FGL2/Prothrombinase Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FGL2/Prothrombinase rabbit polyclonal antibody |
Gene Name: | Fibroleukin |
Synonyms: | Cytotoxic T-lymphocyte-specific protein, Fibrinogen-like protein 2, Prothrombinase, Fgl2, Fiblp, pT49, T49, fibrinogen like 2 |
Immunogen: | Recombinant protein corresponding to Mouse FGL2/Prothrombinase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 64 kDa |
Uniprot ID: | Q14314 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | Raji, HepG2, SW480 |
Background
FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.
Images
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Western blot analysis of FGL2 (GB111587) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
