Reactivity: | M |
Applications: | FC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Endoglin |
Synonyms: | Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1 |
Immunogen: | Recombinant protein corresponding to Mouse CD105 |
Uniprot ID: | Q63961 |
Isotype: | IgG |
Conjugation | FITC |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
FC | Mouse | 1: 100-1: 300 | bend.3 |
Background
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis.
Required for normal structure and integrity of adult vasculature (By similarity).
Regulates the migration of vascular endothelial cells.
Required for normal extraembryonic angiogenesis and for embryonic heart development.
May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
Images
Flow cytometric analysis of CD105. | |
Flow cytometric analysis of CD105. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |