Reactivity: | H |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FKBP12 rabbit polyclonal |
Gene Name: | Peptidyl-prolyl cis-trans isomerase FKBP1A |
Synonyms: | 12 kDa FK506 binding protein, 12 kDa FKBP, FK506 binding protein 1A, FKBP 12, FKBP 1A, FKBP1, FKBP12, FKBP12C, FKBP1A, Immunophilin FKBP12, PKC12, PKCI2, PPIASE, PPIase FKBP1A, Rotamase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FKBP12 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 1500-1: 3000 | colon cancer, esophageal cancer, esophagus |
Background
FKBP1A(FK506-binding protein 1A) is also named as FKBP1, FKBP12 and belongs to the FKBP-type PPIase family.It keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Images
Immunohistochemistry analysis of paraffin-embedded human colon cancer using FKBP12 (GB113132) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using FKBP12 (GB113132) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin-embedded human esophagus using FKBP12 (GB113132) at dilution of 1: 3000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |