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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FLIP rabbit polyclonal antibody |
Gene Name: | CASP8 and FADD-like apoptosis regulator |
Synonyms: | CASH, Cflar, CFLAR, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASP8 and FADD like apoptosis regulator |
Immunogen: | Recombinant protein corresponding to Mouse FLIP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 55 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | O15519, O35732 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | kidney, heart |
Background
CASP8 and FADD-like apoptosis regulator is a protein encoded by the CFLAR gene. It is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Images
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Western blot analysis of CASH (GB11817) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
