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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Forkhead box protein O1 |
Synonyms: | FOXO1, FKH1, FKHR, FOXO1A, forkhead box O1 |
Immunogen: | Recombinant protein corresponding to Mouse FOXO1 |
Uniprot ID: | Q9R1E0 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | colon, esophagus cancer, heart, liver, lung, pancreas, spleen, testis |
Background
FOXO1 is a transcription factor that plays important roles in regulation ofgluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. It is primarily regulated through phosphorylation on multiple residues; its transcriptional activity is dependent on its phosphorylation state.
Images
| Immunohistochemistry of paraffin embedded human colon using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded human esophagus cancer using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse heart using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse testis using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat liver using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat pancreas using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat spleen using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat testis using FOXO1 (GB12286) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
