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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FTS rabbit polyclonal antibody |
Gene Name: | AKT-interacting protein |
Synonyms: | Fused toes protein, Aktip, Fif, Ft1, Fts |
Immunogen: | Recombinant protein corresponding to Mouse FTS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 33 kDa |
Uniprot ID: | Q9H8T0, Q64362, Q5FVH4 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 250-1: 500 | brain |
Background
This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
Images
 | Western blot analysis of AKTIP (GB112366) at dilution of 1: 250 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
