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Anti-FUBP1/FBP Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FUBP1/FBP rabbit polyclonal antibody |
Gene Name: | Far upstream element-binding protein 1 |
Synonyms: | DNA helicase V, FBP, FUBP, FUBP1, FUSE binding protein 1, hDH V |
Immunogen: | Recombinant protein corresponding to Mouse FUBP1/FBP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 69 kDa |
Observed MW. | 69 kDa |
Uniprot ID: | Q91WJ8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 700-1: 1400 | brain, lung |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | testis, pancreas |
Background
FUBP1 also termed as FBP and FUSE-binding protein 1 is 644 amino-acid protein, which localizes in the nucleus. FUBP1 binds to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter and regulates the MYC expression, indicating that FBP1 functions as a growth-dependent regulator of c-Myc expression. FUBP1 binds to FUSE, and PUF60, and forms a stable tripartite complex, which represses activated but not basal c-myc transcription after transcription initiation by delaying promoter escape. FUBP1 may be acting both as activator and repressor of transcription.
Images
 | Western blot analysis of FUBP1 (GB114017) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded mouse testis using FUBP1 (GB114017) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded rat testis using FUBP1 (GB114017) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded rat pancreas using FUBP1 (GB114017) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
