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Anti-Factor B Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Factor B rabbit polyclonal antibody |
Gene Name: | Complement factor B |
Synonyms: | C3/C5 convertase, Cfb, Bf, H2-Bf, AHUS4, Properdin factor B, Glycine-rich beta glycoprotein, Complement Factor B, BFD |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Factor B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 85 kDa |
Observed MW. | 69/85 kDa |
Uniprot ID: | P04186 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | liver |
Background
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Images
 | Western blot analysis of Factor-B (GB112213) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
