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Anti-Fibronectin Mouse mAb (100 μl)
| Reactivity: | H |
| Applications: | IHC |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Fibronectin |
Synonyms: | FN, Fn1, CIG, FINC, Migration stimulating factor, MSF, GFND |
Immunogen: | Recombinant protein corresponding to Mouse Fibronectin |
Uniprot ID: | P02751 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
IHC/IF | Human | 1: 200-1: 400 | cholangiocarcinoma, esophageal carcinoma |
Background
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Images
| Immunohistochemistry analysis of paraffin-embedded human cholangiocarcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37°C temperature. |
| Immunohistochemistry analysis of paraffin-embedded human esophageal carcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37°C temperature. |
| Immunohistochemistry analysis of paraffin-embedded human gastric carcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37°C temperature. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
