Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Filaggrin rabbit polyclonal antibody |
Gene Name: | Filaggrin |
Synonyms: | Flg, ATOD2, Epidermal filaggrin, Profilaggrin, Filaggrin precursor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Filaggrin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 36 kDa |
Observed MW. | 44 kDa |
Uniprot ID: | P11088 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 250-1: 500 | skin |
Background
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.
Images
Western blot analysis of Filaggrin (GB112010) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |