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Anti-GATA1 Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Erythroid transcription factor |
Synonyms: | ERYF1, Erythroid transcription factor, GATA 1, GATA binding factor 1, GATA1, GF 1, GF1, NF E1 DNA binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GATA 1 |
Uniprot ID: | P17679 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
IHC/IF | Rat | 1: 150-1: 300 | testis, liver, bone |
Background
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS.
Images
| Immunohistochemistry analysis of paraffin embedded rat bone using GATA1 (GB115594) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat liver using GATA1 (GB115594) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat testis using GATA1 (GB115594) at dilution of 1: 150 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
