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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GDF6 rabbit polyclonal |
Gene Name: | Growth/differentiation factor 6 |
Synonyms: | GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16, Gdf16, MCOPCB6, MCOP4, LCA17 |
Immunogen: | Recombinant protein corresponding to Mouse GDF6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 1000 | spinal cord, brain, fetal rat |
IF | Mouse, Rat | 1: 500-1: 1000 | brain, hippocampus, spinal cord, fetal rat |
Background
GDF6 is a growth differentiation factor (GDFs), which are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse spinal cord using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat spinal cord using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat fetal rat using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse fetal rat using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using GDF6 (GB111654) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using GDF6 (GB111654) at dilution of 1: 650 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse hippocampus using GDF6 (GB111654) at dilution of 1: 650 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse spinal cord using GDF6 (GB111654) at dilution of 1: 650 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse fetal rat using GDF6 (GB111654) at dilution of 1: 650 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
