Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GGNBP2 rabbit polyclonal antibody |
Gene Name: | Gametogenetin-binding protein 2 |
Synonyms: | Dioxin-inducible factor 3, DIF-3, Protein ZNF403, Ggnbp2, Zfp403, Znf403, LCRG1, LZK1 |
Immunogen: | Recombinant protein corresponding to Mouse GGNBP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 79 kDa |
Observed MW. | 79 kDa |
Uniprot ID: | Q5SV77, Q6GVH5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | stomach, skeletal muscle |
Background
LCRG1 is a 697 amino acid protein that may be involved in spermatogenesis. LCRG1 interacts with gametogenetin, a protein primarily expressed in testis and ovary. Localized in the cytoplasm, LCRG associates with vesicular structures. LCRG1 is expressed in brain, placenta, lung, liver and kidney, with highest levels found in heart, pancreas and skeletal muscle. LCRG1 is strongly down-regulated in 40% of primary laryngeal carcinoma and in 6 of 10 various cancer cell lines. Phosphorylated on Serine 360, LCRG1 exists as three isoforms produced by alternative splicing events.
Images
Western blot analysis of GGNBP2 (GB112566) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |