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Anti-GLUD1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GLUD1 rabbit polyclonal antibody |
Gene Name: | Glutamate dehydrogenase 1, mitochondrial |
Synonyms: | GDH, GDH 1, GDH1, GLUD, GLUD1, glutamate dehydrogenase 1, EC 1.4.1.3, Gdh-X, MRG-2, Memory-related gene 2 protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GLUD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum, Mitochondrion |
Predicted MW. | 61 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, kidney, skin |
IHC/IF | Human | 1: 400-1: 1200 | colon cancer, lung cancer, liver cancer, kidney, placenta |
Background
Human glutamate dehydrogenase (GDH), an enzyme central to the metabolism of glutamate, is known to exist in housekeeping and nerve tissue-specific isoforms encoded by the GLUD1 and GLUD2 genes, respectively. It catalyses the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, thus interconnecting amino acid and carbohydrate metabolism. GLUD1 might contribute to the formation of specific synapses in the hippocampus such as those formed by the projecting neurons of the entorhinal cortex.
Images
 | Western blot analysis of GLUD1 (GB113833) at dilution of 1: 2000 |
 | Immunohistochemistry analysis of paraffin-embedded human colon cancer using GLUD1 (GB113833) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded human lung cancer using GLUD1 (GB113833) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded human kidney using GLUD1 (GB113833) at dilution of 1: 1200 |
 | Immunohistochemistry analysis of paraffin-embedded human placenta using GLUD1 (GB113833) at dilution of 1: 1200 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human kidney using GLUD1 (GB113833) at dilution of 1: 1200 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human liver cancer using GLUD1 (GB113833) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
