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Anti-GOLPH3/MIDAS Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Golgi phosphoprotein 3 |
Synonyms: | Coat protein GPP34, Golph3, Gpp34, GOPP1, MIDAS, Mitochondrial DNA absence factor, Coat protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GOLPH3/MIDAS |
Uniprot ID: | Q9CRA5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 34 kDa / 34 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 100-1: 500 | liver |
Background
GOLPH3 (also called GPP34, GMx33, MIDAS, or yeast Vps74p) is a 34-kDa Golgi-associated protein conserved from yeast to human. GOLPH3 binds to PtdIns(4)P-rich trans-Golgi membranes and MYO18A conveying a tensile force required for efficient tubule and vesicle formation . GOLPH3 has been recently demonstrated as a novel oncoprotein amplified in various types of human malignancies, including melanoma, breast, non-small cell lung cancer, gliomas and connective tissue tumors . Enhanced activation of mTOR signalling represents a molecular basis for the oncogenic activity of GOLPH3.
Images
| Western blot analysis of GOLPH3/MIDAS (GB111798) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
