Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Probable G-protein coupled receptor 19 |
Synonyms: | Gpr19, GPR NGA, G protein coupled receptor GPR19 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GPCR GPR19 |
Uniprot ID: | Q61121 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 48 kDa / 55 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex |
Background
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR19 is an orphan receptor found primarily in the central nervous system. GPR19 was also found in ovary and testis and in human embryonic stem cells. GPR19 has been postulated to play a role in cancer development and increased levels of GPR19 mRNA were found in metastatic melanoma, small cell lung carcinoma and pancreas islet cell carcinoma.
Images
Western blot analysis of GPR19 (GB111788) at dilution of 1: 1000 Lane 1: Mouse brain tissue lysate Lane 2: Mouse cortex tissue lysate Lane 3: Rat brain tissue lysate Lane 4: Rat cortex tissue lysate |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |