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Anti-GRIM19 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GRIM19 rabbit polyclonal antibody |
Gene Name: | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 |
Synonyms: | Cell death regulatory protein GRIM-19, Complex I-B16.6, CI-B16.6, GRIM-19, NADH-ubiquinone oxidoreductase B16.6 subunit, Ndufa13, Grim19 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GRIM19 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 17 kDa |
Observed MW. | 17 kDa |
Uniprot ID: | Q9ERS2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 3000-1: 6000 | heart, kidney, liver |
Background
A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.
Images
 | Western blot analysis of Ndufa13 (GB112555) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
