Your shopping cart is empty!
| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GRP94 rabbit polyclonal antibody |
Gene Name: | Endoplasmin |
Synonyms: | Hsp90b1, HSP90B1, ECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1, heat shock protein 90kDa beta family member 1, heat shock protein 90 beta family member 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human GRP94 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | P14625 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 500-1: 2000 | breast cancer, colon, colon cancer, lymph node, lymphoma, ovarian cancer |
Background
Glucose regulated protein 94 (GRP 94) is a resident protein of the endoplasmic reticulum (ER) and is induced by the accumulation of unfolded proteins suggesting that it might associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP 94 and other resident ER proteins including GRP 78 and protein disulfide isomerase (PDI).
Images
 |
Immunohistochemistry of paraffin embedded human colon using GRP94 (GB11826) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human colon cancer using GRP94 (GB11826) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human lymphoma using GRP94 (GB11826) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded human breast cancer using GRP94 (GB11826) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded human colon cancer using GRP94 (GB11826) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded human ovarian cancer using GRP94 (GB11826) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded mouse lymph node using GRP94 (GB11826) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
