Reactivity: | H,M,R & H,M,R |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GSK3 beta rabbit polyclonal |
Gene Name: | Glycogen synthase kinase-3 beta |
Synonyms: | GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta |
Immunogen: | Recombinant protein corresponding to Mouse GSK3β |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: | P49841, Q9WV60 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 1000-1: 3000 | ovary, brain, colon, breast carcinoma |
IF | Human, Mouse, Rat | 1: 500-1: 1000 | ovary, brain, colon, breast carcinoma |
Background
Glycogen synthase kinase-3 (GSK-3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and an inactivating agent of glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. It might be a new therapeutic target for ischemic stroke.
Images
Immunohistochemistry analysis of paraffin-embedded mouse ovary using GSK3β(GB11835) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using GSK3β(GB11835) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using GSK3β(GB11835) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using GSK3β(GB11835) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma using GSK3β(GB11835) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |