Reactivity: | M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GSTM2 rabbit polyclonal |
Gene Name: | Glutathione S-transferase Mu 2 |
Synonyms: | GST 5-5, GST class-mu 2, Glutathione S-transferase pmGT2, Gstm2, GTHMUS, GSTM, GST4 |
Immunogen: | Recombinant protein corresponding to Mouse GSTM2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 26 kDa |
Observed MW. | 26 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | liver, testis, lung |
IHC | Mouse, Rat | 1: 2000-1: 4000 | skeletal muscle |
Background
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic.
Images
Western blot analysis of GSTM2 (GB113127) at dilution of 1: 2000 | |
Western blot analysis of GSTM2 (GB113127) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using GSTM2 (GB113127) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using GSTM2 (GB113127) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |