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Anti-Glutamine Synthetase Mouse mAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Glutamine synthetase |
Synonyms: | cell proliferation-inducing protein 59, GLNA, GLNS, GLUL, Glutamate ammonia ligase, Glutamate decarboxylase, Glutamine synthetase, GS, PIG43, PIG59, Proliferation inducing protein 43, Palmitoyltransferase GLUL |
Immunogen: | Recombinant protein corresponding to Human Glutamine Synthetase |
Uniprot ID: | P15104 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 42 kDa / 42 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1:500-1:1000 | liver, testis, brain |
IHC/IF | Human, Mouse, Rat | 1: 3000-1: 6000 | liver, liver cancer, glioma, brain |
Background
Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation.
Images
| Western blot analysis of Glul (GB121177) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human liver using GLUL (GB121177) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat liver using GLUL (GB121177) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using GLUL (GB121177) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded human glioma using GLUL (GB121177) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using GLUL (GB121177) at dilution of 1: 6000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
