Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HAND1 rabbit polyclonal antibody |
Gene Name: | Heart- and neural crest derivatives-expressed protein 1 |
Synonyms: | Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast, Thing-1, Th1, Hand1, Ehand, Hxt, Thing1 |
Immunogen: | Recombinant protein corresponding to Mouse HAND1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q64279, P97832 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | heart, placenta |
Background
HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease.
Images
Immunohistochemistry of paraffin embedded mouse placenta using HAND1 (GB111824) at dilution of 1:1000 (300x lens) | |
Immunohistochemistry of paraffin embedded mouse heart using HAND1 (GB111824) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat placenta using HAND1 (GB111824) at dilution of 1:1000 (300x lens) | |
Immunofluorescence of paraffin embedded mouse placenta using HAND1 (GB111824) at dilution of 1:500 (300x lens) | |
Immunofluorescence of paraffin embedded rat placenta using HAND1 (GB111824) at dilution of 1:500 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |