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Anti-HC-II Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Heparin cofactor 2 |
Synonyms: | Heparin cofactor II, HC-II, Protease inhibitor leuserpin-2, Serpin D1, Hcf2, Hcii, HLS2, Leuserpin 2 |
Immunogen: | Recombinant protein corresponding to Mouse HC-II |
Uniprot ID: | P49182 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 54 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1:250-1:500 | testis, liver |
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | spleen, testis |
Background
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
Images
| Western blot analysis of HC-II (GB112225) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded mouse testis using serpind1 (GB112225) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded mouse spleen using serpind1 (GB112225) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
