Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HDAC6 rabbit polyclonal antibody |
Gene Name: | Histone deacetylase 6 |
Synonyms: | HDAC6, CPBHM, HD6, PPP1R90, JM21, Histone deacetylase 6 |
Immunogen: | Recombinant protein corresponding to Mouse HDAC6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 131 kDa |
Observed MW. | 131 kDa |
Uniprot ID: | Q9UBN7, Q9Z2V5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HepG2, MCF7, HCT116 |
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Images
 |
Western blot analysis of HDAC6 (GB11558) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
