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Anti-HDAC8 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HDAC8 rabbit polyclonal antibody |
Gene Name: | Histone deacetylase 8 |
Synonyms: | HD8, Hdac8, CDA07, CDLS5, Histone deacetylase like 1, MRXS6, RPD3, WTS |
Immunogen: | Recombinant protein corresponding to Mouse HDAC8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 45 kDa |
Uniprot ID: | Q8VH37, B1WC68 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, brain |
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.
Images
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Western blot analysis of HDAC8 (GB111432) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
