Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HHLA2 rabbit polyclonal antibody |
Gene Name: | HERV-H LTR-associating protein 2 |
Synonyms: | Human endogenous retrovirus-H long terminal repeat-associating protein 2, HHLA2, B7H7 |
Immunogen: | Recombinant protein corresponding to Human HHLA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9UM44 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 800 | HeLa, MDAMB231, A549 |
Background
Human endogenous retroviruses (HERVs) are repetitive elements that are derived from ancient germline retroviral infections. Due to their ability to move and insert next to certain genes and alter expression patterns, HERVs have been linked to several chronic diseases such as nervous systemic diseases, cancer, autoimmune and connective tissue diseases. The HERV-H family is the most abundant HERV family and has been implicated in the expression of a variety of adjacent genes. Proteins belonging to the HERV-H family are divided into one major and two minor groups based on sequence divergence.
Images
Western blot analysis of HHLA2 (GB112461) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |