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Anti-HJURP Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Holliday junction recognition protein |
Synonyms: | FAKTS, FLEG1, hFLEG1, HJURP, Up regulated in lung cancer 9, URLC9 |
Immunogen: | Recombinant protein corresponding to Human HJURP |
Uniprot ID: | Q8NCD3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 84 kDa / 64 kDa |
Product Usage Information
WB | Human | 1: 300-1: 800 | 293T, A549, MCF7 |
Background
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Images
| Western blot analysis of HJURP (GB114568) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
