Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HLA-DOA rabbit polyclonal antibody |
Gene Name: | HLA class II histocompatibility antigen, DO alpha chain |
Synonyms: | MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA, HLA-DOA, HLA-DNA, HLA-DZA, DO alpha chain precursor, HLADZ, Lymphocyte antigen, HLA DNA, HLA D0 alpha |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human HLA-DOA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28kDa |
Observed MW. | 35kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1500 | Raji, Jurkat |
Background
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
Images
Western blot analysis of HLADOA (GB113229) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |