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Anti-hnRNP C1 + C2/HNRNPC Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Heterogeneous nuclear ribonucleoproteins C1/C2 |
Synonyms: | hnRNP C1/C2, Hnrnpc, Hnrpc, SNRPC, Nuclear ribonucleoprotein particle C1 protein, Heterogeneous nuclear ribonucleoprotein C |
Immunogen: | Recombinant protein corresponding to Mouse hnRNP C1 + C2/HNRNPC |
Uniprot ID: | Q9Z204 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 34 kDa / 42 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, kidney, cerebellum |
IHC/IF | Mouse, Rat | 1: 100-1: 600 | cerebellum |
Background
HNRNPC, also named as Heterogeneous nuclear ribonucleoproteins C1/C2, is a 306 amino acid protein, which contains 1 RRM (RNA recognition motif) domain and belongs to the RRM HNRPC family. HNRNPC localizes in the nucleus. It binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. HNRNPC may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. HNRNPC can act as a tetramer and is involved in the assembly of 40S hnRNP particles and plays a role with CSDE1 in internal initiation of translation during mitosis.
Images
| Western blot analysis of hnRNPC (GB111815) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse cerebellum using hnRNPC (GB111815) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat cerebellum using hnRNPC (GB111815) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
